We extend our deepest gratitude to the generous individuals who supported us in January.
With sincere thanks to: ✨ Richard A. Cohn ✨ Roshan P. George ✨ Ann P. Guillot ✨ Darla Jones ✨ Megan Lo ✨ Melissa R. Meyers ✨ Asha Moudgil ✨ Kathryn Schubert ✨ Jodi Smith ✨ Agnieszka Swiatecka-Urban ✨ Joy Viola ✨ Adam Weinstein ✨ Lynne P. Yao
Your generosity helps us continue our mission—thank you for being part of our community!
History Project: 50th anniversary of IPNA
In honor of the 50th Anniversary of the upcoming IPNA Congress, take a look at the program and photos from the first such international meeting in pediatric nephrology which set the stage for the eventual development of IPNA and its Congresses.
Call for Volunteers: 2025 ASPN Board Review Course
We are beginning to plan the 2025 ASPN Board Review Course and are seeking volunteers to join the ASPN Board Review Editorial Board.
We need members to assist with:
Reviewing and updating content specifications: Ensure the course content aligns with the latest advancements and board certification requirements.
Reviewing current questions: Evaluate existing questions for accuracy, clarity, and relevance.
Developing new questions: Contribute original, high-quality questions that effectively assess knowledge in pediatric nephrology. See the current list of questions below. We are looking for more questions in all sections, but particularly the ones with fewer or no questions.
If you are interested in contributing to the 2025 ASPN Board Review Course, please contact Christine Sethna at csethna@northwell.edu. Please specify the area(s) in which you would like to assist. The deadline for return of materials is May 1, 2025.
Thank you for your commitment to ASPN and pediatric nephrology education.
Sincerely,
ASPN Planning Committee
Open to all: Find out how YOU can take advantage of the Pediatric Centers of Excellence in Nephrology to advance your research! In-Person or Virtual
The NIDDK is pleased to announce the 2025 Scientific Symposium “Promoting Research in Childhood Kidney Disease,” which will be hosted by the Pediatric Centers of Excellence in Nephrology (PCEN). This meeting will be an opportunity for you to hear about resources you can access from the PCENs, updates on PCEN science, collaborative opportunities with PCEN researchers, mentorship and funding opportunities, and a hands-on workshop on cutting-edge technologies to advance your research.
Date: March 6, 2025, 9 am–3 pm EST
Hybrid Format: Virtually & in person at NIH in Bethesda, MD
Attending IPNA Congress in Cape Town? Donate Your Expired Dialysis Catheters!
If you are planning to attend the IPNA Congress in Cape Town in February, there is an opportunity to donate PD & HD catheters that are 'usable' - past their expiry dates, but still in their sterile packaging and with the full insertion kit that comes with each catheter. All dialysis catheters, PD and HD, temporary and permanent, and of all sizes will be useful. Also, Hickmann lines and similar catheters are needed. We can’t use them at our centers, but they will be useful to Saving Young Lives so bring them along with you! More information here: https://www.theisn.org/programs/saving-young-lives-project
ASPN Announces Trainee Travel Grants for 2025 IPNA Congress
The ASPN Foundation is offering travel grants of $1500 to American and Canadian trainees currently enrolled in ACGME- or RCPSC-approved pediatric nephrology training programs who have submitted an abstract to the 20th IPNA Congress being held in Cape Town, South Africa February 19-23, 2025. The ASPN Foundation will provide travel grants to a limited number of trainees to support their attendance at the meeting.
To be considered for a travel grant, please complete this online form providing a copy of your abstract and abstract submission confirmation. Travel grants will be awarded on a rolling basis until the designated funds are exhausted. You will receive notification within 2 weeks of submission.
Visit the IPNA Congress website for additional details about the meeting and registration.
This will be an unparalleled opportunity for trainees to attend the premier international meeting in our field, broaden their exposure to pediatric nephrology concepts and issues and deepen their understanding of global pediatric nephrology concerns and opportunities.
Volunteer Opportunity
We are looking for a podcast co-host for the 2025 ASPN Sediment podcast featuring PAS pediatric nephrology sessions. Please email Emily Zangla (emily.zangla@sanfordhealth.org) if you are interested!
Do you have successes to share in upcoming KIDney Briefs?
12:00 – Session Welcome Chairs Grainne Walsh, ANP, Evelina London Children’s Hospital, UK & Ilana Webber, Lecturer, University of Cape Town, South Africa
12:05-12:30 – Empowering parents – Nurses are key! Professor Minette Coetzee, Harry Crossley Children’s Nursing Development Unit, University of Cape Town, South Africa
12:30-13:15 Introducing our IPNA Baby Lulama Baby Lulama has CKD – Case study & panel discussion
13:15-13:20 Tea/Stretch break
13:20-14:20 Toddler Lulama – The way forward – KRT or conservative management – Case study & panel
14:20-14:30 Tea/stretch Break
14:30-15:15 Lulama, now a Teen and now a Kidney transplant recipient – case study & panel Young Adult issues, adherence/transition
15:15-15:50 Child & Family Experience Lived experience of a child & parent from Red Cross War Memorial Children’s Hospital, Cape Town, South Africa
5th International Symposium on Acute Kidney Injury in Children September 26-28, 2025
Symposium programming will provide an interactive educational platform for physicians, nurses and affiliated healthcare professionals who care for children with, or at-risk-for, AKI. Medical specialties will represent nephrology, critical care medicine, cardiology and neonatology. https://www.cincyhearteducationseries.org/akisymposium
A Message from our CLB partner, Vertex
Enrolling Pediatric Patients in APOL1-mediated Kidney Disease Trial
Studies have demonstrated that people with APOL1 genetic variants, G1 and G2, have a greater risk of developing proteinuria and chronic kidney disease (CKD).These APOL1 variants are associated with a more aggressive CKD course with a faster decline to end-stage kidney disease (ESKD). APOL1 genetic variants have toxic gain of function activity and are more likely to occur in patients of African ancestry, contributing to disparities in health outcomes for CKD.
The AMPLITUDE Clinical Study, sponsored by Vertex Pharmaceuticals, is evaluating an investigational product to see if it will block APOL1-mediated toxic effects in the kidney, leading to decreased proteinuria and improved clinical outcomes. The study includes an APOL1 genotype test to determine which genetic variants, if any, a patient may have.
With your help, we can support further testing and development of a potential treatment for patients with proteinuric kidney disease due to APOL1 genetic variants. This Phase 2/3 study is now enrolling patients that are 10 years of age and older. Please see a list of active participating pediatric locations:
Do you have a patient who might be a good fit? Please see below for the key inclusion and exclusion criteria for this study.The full list of criteria is available on ClinicalTrials.gov via link above.
Key Inclusion Criteria:
APOL1 genotype of G1/G1, G2/G2, or G1/G2
Proteinuric kidney disease
Key Exclusion Criteria:
Solid organ or bone marrow transplant
Uncontrolled hypertension
History of diabetes mellitus
Known underlying cause of kidney disease including but not limited to sickle cell disease
If you’d like to refer a potential participant, feel free to connect directly with a study center if you already have referral connections, or you can provide the link to our patient facing website that includes pre-screeninghttps://amplitudeclinicalresearchstudy.com/.
